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TOPIC 08 · EMERGENCY & CRITICAL CARE

Adult CPR: AHA 2025 Guidelines, Nursing Care & 12 Scenario MCQs

Revise recognition, compressions, defibrillation, medicines, investigations and nursing care before, during and after adult resuscitation.

22 October 2026 · AHA 2025 guidelines · 12 original scenario MCQs · No login needed

100–120compressions / min
≥5 cmadult depth; avoid >6 cm
30:2without advanced airway
10/minadvanced-airway breaths

1. What CPR does

Cardiopulmonary resuscitation (CPR) supplies temporary circulation and oxygen delivery during cardiac arrest. BLS combines recognition, compressions, ventilation and AED use; ALS adds rhythm-directed treatment, vascular access, medicines and airway management.

This page covers adult BLS, including people with signs of puberty. Infants and prepubertal children have a separate page. ROSC means return of spontaneous circulation: the patient has regained effective circulation, but still needs intensive assessment.

AHA 2025: Adult Basic Life Support · AHA 2025: Adult healthcare-professional BLS algorithm

2. Indications: recognise arrest quickly

  • An unresponsive patient has no normal breathing, or only gasps, and no definite pulse within a healthcare professional’s 10-second check: activate the code and start CPR.
  • An organised ECG does not prove circulation. An organised rhythm without a pulse is pulseless electrical activity (PEA).
  • If a definite pulse remains but breathing is absent/inadequate, give rescue breaths every 6 seconds (10/min); reassess the pulse every 2 minutes. Start compressions if the pulse is lost.

AHA 2025: Adult healthcare-professional BLS algorithm · AHA 2025: Adult Advanced Life Support

3. When CPR is not started or is stopped

CPR is an emergency intervention, not an elective procedure with routine laboratory contraindications. Follow local law, documented care decisions and the responsible clinician’s direction.

  • A valid, applicable DNACPR/advance-care decision, objective signs of irreversible death, or serious danger to rescuers can justify withholding CPR under the relevant policy.
  • Do not withhold solely because of age, pregnancy or fear of rib injury. When the status is uncertain, activate urgent help and follow the emergency policy.
  • After ROSC, stop chest compressions and begin post-arrest care. A trained team makes termination decisions; a nurse should not independently stop because one ETCO₂ value is low or one time limit has passed.

AHA 2025: Ethics and decisions about CPR · AHA 2025: Adult Advanced Life Support

4. Nursing care before / at recognition

  • During routine readiness checks: inspect the crash cart, defibrillator, oxygen, suction, bag-mask equipment and drug expiry dates; know the code-call process.
  • At collapse: check safety and responsiveness; call for help, activate the emergency response and send for the AED. Check breathing and carotid pulse together within 10 seconds.
  • Start immediately on a firm, flat support where effective CPR can be delivered. Use the bed’s CPR mode/backboard when appropriate without a long transfer delay.
  • Allocate compressor, airway, monitor/defibrillator, access/medication and recorder roles. Use closed-loop communication: repeat an instruction, perform it and confirm completion.

AHA 2025: Adult Basic Life Support · AHA 2025: Adult healthcare-professional BLS algorithm

5. Nursing care during CPR

ComponentAdult approach
Compressions100–120/min; depth at least 5 cm, avoiding excessive depth greater than 6 cm. Lower half of sternum; two hands; full recoil.
Ventilation without advanced airway30:2. Give each breath over about 1 second, just enough for visible chest rise. Prefer a two-person bag-mask seal when staff allow.
Advanced airwayContinuous compressions; 1 breath every 6 seconds. Confirm and monitor tracheal tube position using waveform capnography.
Pauses and fatigueKeep necessary pauses under 10 seconds; switch compressor about every 2 minutes, sooner if tiring. Do not lean between compressions.
Monitor and recordRhythm checks about every 2 minutes; record collapse, CPR, shocks, doses, airway and ROSC times. Low/falling ETCO₂ prompts a CPR-quality review.

Attach pads while compressions continue. Clear everyone before shock delivery; manage oxygen safely. Resume compressions immediately after a shock, rather than pausing to look for a pulse. Give oxygen during CPR and avoid excessive bagging.

AHA 2025: Adult Basic Life Support · AHA 2025: Adult cardiac arrest algorithm

6. Rhythm-directed care and reversible causes

VF / pulseless VT: shockablePEA / asystole: nonshockable
Defibrillate promptly, then resume CPR for 2 minutes. Obtain IV access first; use IO if IV is unsuccessful/not feasible.Continue CPR and give epinephrine as soon as possible. Confirm apparent asystole with equipment/lead checks without a prolonged pause.
If VF/pVT persists after the second shock, epinephrine is given during the next CPR cycle; after the third shock, amiodarone or lidocaine is considered.Do not shock PEA or asystole. Reassess rhythm and treat a new shockable rhythm if it develops.

Adult shock energy: biphasic manufacturer setting (commonly 120–200 J initially); if unknown, use the maximum available setting. Later shocks are at least equivalent; higher doses may be considered. Monophasic: 360 J.

Search for reversible causes: hypovolaemia, hypoxia, acidosis, hypo-/hyperkalaemia, hypothermia; tension pneumothorax, tamponade, toxins, pulmonary thrombosis and coronary thrombosis. Assign someone to check the history and likely cause while CPR continues.

AHA 2025: Adult Advanced Life Support · AHA 2025: Adult cardiac arrest algorithm

7. Drugs: indication, dose and nursing checks

MedicineWhen / adult IV or IO doseNursing priority
Epinephrine (adrenaline)1 mg every 3–5 minutes during cardiac arrest. PEA/asystole: as soon as possible; VF/pVT: after initial defibrillation attempts.Use the locally supplied arrest preparation; document each dose and avoid duplicate administration.
AmiodaroneShock-refractory VF/pVT: 300 mg bolus, then 150 mg if indicated.Not a treatment for asystole. Continue CPR and rhythm-directed shocks.
Lidocaine: alternativeFirst 1–1.5 mg/kg, then 0.5–0.75 mg/kg if indicated.Use as the protocol-selected alternative to amiodarone; check cumulative dosing.
Cause-specific treatmentMagnesium for torsades when indicated; calcium, bicarbonate, glucose or antidotes only for an appropriate identified/suspected cause and order.Calcium, bicarbonate and magnesium are not routine drugs for every arrest. Atropine is not routine treatment of PEA/asystole.
After ROSCTitrated fluids, vasopressor/inotrope, analgesia/sedation or antiseizure treatment may be ordered.Monitor BP, rhythm, perfusion and response. The repeated arrest epinephrine bolus is not a routine post-ROSC prescription.

AHA 2025: Adult cardiac arrest algorithm · AHA 2025: Adult Advanced Life Support · AHA 2025: Adult and paediatric special circumstances

8. Investigations: before, during and after

StageAssessment / testWhy it helps
Before or at collapseReview available history, medicines and trends, while immediately assessing responsiveness, breathing and pulse.Recognise deterioration/arrest; recent potassium results or dialysis history may suggest a cause.
During CPRMonitor/AED rhythm; waveform ETCO₂ after advanced airway; glucose, blood gas and electrolytes when available without delaying care.Guide shocks, review ventilation/perfusion and identify reversible causes. Blood results are interpreted with the clinical picture.
During CPR, selected casesSkilled point-of-care ultrasound only if it does not prolong interruptions.May support identification of tamponade or another treatable cause; cannot replace pulse/rhythm assessment or justify extra pauses.
After ROSC12-lead ECG as soon as feasible; ABG, glucose, potassium/magnesium, lactate and renal function; other blood tests according to cause.Assess ischaemia, gas exchange, perfusion, metabolic disturbance and organ injury.
After ROSC, as indicatedEcho; chest imaging for airway/lung complications; CT or coronary evaluation; EEG for suspected seizures/persistent impaired consciousness.Investigate the likely cause and complications. No single scan or immediate neurological exam alone determines prognosis.

AHA 2025: Adult Advanced Life Support · AHA 2025: Adult post-cardiac arrest care

9. Nursing care after ROSC

  • Reassess ABCs, secure and recheck the airway, continue ECG/BP/SpO₂ monitoring and arrange critical-care transfer.
  • Initially use 100% oxygen until a reliable measurement is available; then titrate toward SpO₂ 90–98%. In the comatose adult, generally target PaCO₂ 35–45 mm Hg. Check an ABG when ventilated.
  • Avoid hypotension: maintain MAP at least 65 mm Hg, with patient-specific adjustment by the team. Trend lactate, urine output and peripheral perfusion.
  • Measure core temperature; follow prescribed temperature control and fever prevention. Monitor glucose and electrolytes, skin, lines and possible CPR injuries.
  • Assess consciousness and seizures, recognising sedation confounds examination. Provide family updates, accurate handover and a team debrief.

AHA 2025: Adult post-cardiac arrest care

10. Scenario-based MCQs

Choose one best answer before opening the explanation. These are original Nursing Medium practice questions, not official AHA examination items.

QUESTION 01

A nurse finds a patient unresponsive, gasping and without a definite carotid pulse after 10 seconds. What should happen next?

  1. Wait for a 12-lead ECG
  2. Activate the code and start CPR
  3. Give oral glucose
  4. Transfer to CT before treating
Show answer & rationale

Correct answer: B. Activate the code and start CPR

Rationale: Gasps do not count as normal breathing. An uncertain pulse must not lead to a prolonged assessment delay.

AHA 2025: Adult healthcare-professional BLS algorithm

QUESTION 02

An adult has a definite pulse of 78/min but is apnoeic. Which initial breathing plan fits adult BLS?

  1. Compressions only
  2. One breath every 2 seconds
  3. No ventilation while a pulse is present
  4. One breath every 6 seconds, reassessing the pulse
Show answer & rationale

Correct answer: D. One breath every 6 seconds, reassessing the pulse

Rationale: This is respiratory arrest with a pulse. Provide about 10 breaths/min and watch for loss of circulation.

AHA 2025: Adult healthcare-professional BLS algorithm

QUESTION 03

During CPR the compressor works at 145/min and leans on the chest between compressions. What correction is best?

  1. Use 100–120/min and allow full recoil
  2. Increase to 160/min
  3. Keep leaning to maintain pressure
  4. Pause for a full minute
Show answer & rationale

Correct answer: A. Use 100–120/min and allow full recoil

Rationale: Excessive speed and incomplete release reduce effective compression quality. Correct both technique problems.

AHA 2025: Adult Basic Life Support

QUESTION 04

Two nurses perform adult CPR without an advanced airway. Which compression-to-breath ratio should they use?

  1. 15:2
  2. 3:1
  3. 30:2
  4. Continuous compressions with 30 breaths/min
Show answer & rationale

Correct answer: C. 30:2

Rationale: The adult ratio remains 30:2 even with two rescuers until an advanced airway allows asynchronous breaths.

AHA 2025: Adult cardiac arrest algorithm

QUESTION 05

A pulseless adult is in VF and the defibrillator is ready. Which action takes priority?

  1. Wait until epinephrine has been prepared
  2. Give atropine
  3. Check a laboratory potassium first
  4. Deliver a shock promptly, then resume CPR
Show answer & rationale

Correct answer: D. Deliver a shock promptly, then resume CPR

Rationale: A ready shock should not wait for medication preparation. Immediately restart compressions after delivery.

AHA 2025: Adult cardiac arrest algorithm

QUESTION 06

The monitor shows organised complexes, but no pulse is felt. What is the correct approach?

  1. CPR and early epinephrine; investigate causes
  2. Synchronised cardioversion
  3. Observe because electrical activity proves perfusion
  4. Defibrillate every organised rhythm
Show answer & rationale

Correct answer: A. CPR and early epinephrine; investigate causes

Rationale: Organised electrical activity without circulation is PEA, which is nonshockable.

AHA 2025: Adult Advanced Life Support

QUESTION 07

A recorder sees an order for adult arrest epinephrine. Which dose should be read back?

  1. 0.1 mg every 10 minutes
  2. 10 mg once
  3. 1 mg IV/IO every 3–5 minutes
  4. 1 mg/kg every minute
Show answer & rationale

Correct answer: C. 1 mg IV/IO every 3–5 minutes

Rationale: The adult arrest dose is a fixed 1 mg, unlike paediatric weight-based dosing. Record timing to avoid duplication.

AHA 2025: Adult cardiac arrest algorithm

QUESTION 08

VF persists after three shocks and the leader chooses amiodarone. Which first adult arrest dose is correct?

  1. 150 mg as the first dose
  2. 300 mg IV/IO bolus
  3. 5 mg total
  4. 1 mg IV/IO
Show answer & rationale

Correct answer: B. 300 mg IV/IO bolus

Rationale: For shock-refractory adult VF/pVT, the first bolus is 300 mg; a later dose is 150 mg if indicated.

AHA 2025: Adult cardiac arrest algorithm

QUESTION 09

An intubated adult is receiving continuous compressions. Which ventilation plan should be used?

  1. One breath every 6 seconds
  2. Two breaths after every 15 compressions
  3. One breath each second
  4. Stop compressions for every breath
Show answer & rationale

Correct answer: A. One breath every 6 seconds

Rationale: An advanced airway permits continuous compressions with about 10 breaths/min in adults. Avoid overventilation.

AHA 2025: Adult cardiac arrest algorithm

QUESTION 10

A nurse is asked to stop CPR so a blood sample and ultrasound can be completed. What is the best response?

  1. Stop for every investigation
  2. Wait until all results return
  3. Draw blood only after the next shift
  4. Arrange tests in parallel without prolonging pauses
Show answer & rationale

Correct answer: D. Arrange tests in parallel without prolonging pauses

Rationale: Tests can help identify a cause, but should not take priority over circulation and prompt defibrillation.

AHA 2025: Adult Advanced Life Support

QUESTION 11

After ROSC an adult has a reliable SpO₂ of 100% on maximum oxygen. What is appropriate?

  1. Continue maximum oxygen indefinitely
  2. Titrate oxygen toward 90–98%, using reliable measurements
  3. Remove all oxygen immediately
  4. Target 75–80%
Show answer & rationale

Correct answer: B. Titrate oxygen toward 90–98%, using reliable measurements

Rationale: Post-arrest care avoids both hypoxaemia and unnecessary hyperoxaemia. Titrate rather than abruptly remove support.

AHA 2025: Adult post-cardiac arrest care

QUESTION 12

After ROSC, MAP is 54 mm Hg and peripheral perfusion is poor. What should the nurse do?

  1. Treat this as an acceptable adult target
  2. Restart routine arrest epinephrine boluses without review
  3. Escalate and implement prescribed support toward MAP at least 65 mm Hg
  4. Delay intervention until urine output is measured tomorrow
Show answer & rationale

Correct answer: C. Escalate and implement prescribed support toward MAP at least 65 mm Hg

Rationale: Persistent hypotension threatens organ perfusion. Post-ROSC treatment is titrated to haemodynamics, not simply continued arrest boluses.

AHA 2025: Adult post-cardiac arrest care

Sources and guideline version

  1. AHA 2025: Adult Basic Life Support
  2. AHA 2025: Adult healthcare-professional BLS algorithm
  3. AHA 2025: Adult Advanced Life Support
  4. AHA 2025: Adult cardiac arrest algorithm
  5. AHA 2025: Adult post-cardiac arrest care
  6. AHA 2025: Ethics and decisions about CPR
  7. AHA 2025: Adult and paediatric special circumstances

Checked 22 October 2026 against the 2025 AHA CPR/ECC guidelines; paediatric recommendations are jointly developed with the AAP. These independent Nursing Medium study notes are not an AHA course, endorsement or certification. Practise CPR through hands-on training; clinical teams follow the current local protocol and patient-specific orders.