Adult CPR: AHA 2025 Guidelines, Nursing Care & 12 Scenario MCQs
Revise recognition, compressions, defibrillation, medicines, investigations and nursing care before, during and after adult resuscitation.
22 October 2026 · AHA 2025 guidelines · 12 original scenario MCQs · No login needed
100–120compressions / min
≥5 cmadult depth; avoid >6 cm
30:2without advanced airway
10/minadvanced-airway breaths
1. What CPR does
Cardiopulmonary resuscitation (CPR) supplies temporary circulation and oxygen delivery during cardiac arrest. BLS combines recognition, compressions, ventilation and AED use; ALS adds rhythm-directed treatment, vascular access, medicines and airway management.
This page covers adult BLS, including people with signs of puberty. Infants and prepubertal children have a separate page. ROSC means return of spontaneous circulation: the patient has regained effective circulation, but still needs intensive assessment.
An unresponsive patient has no normal breathing, or only gasps, and no definite pulse within a healthcare professional’s 10-second check: activate the code and start CPR.
An organised ECG does not prove circulation. An organised rhythm without a pulse is pulseless electrical activity (PEA).
If a definite pulse remains but breathing is absent/inadequate, give rescue breaths every 6 seconds (10/min); reassess the pulse every 2 minutes. Start compressions if the pulse is lost.
CPR is an emergency intervention, not an elective procedure with routine laboratory contraindications. Follow local law, documented care decisions and the responsible clinician’s direction.
A valid, applicable DNACPR/advance-care decision, objective signs of irreversible death, or serious danger to rescuers can justify withholding CPR under the relevant policy.
Do not withhold solely because of age, pregnancy or fear of rib injury. When the status is uncertain, activate urgent help and follow the emergency policy.
After ROSC, stop chest compressions and begin post-arrest care. A trained team makes termination decisions; a nurse should not independently stop because one ETCO₂ value is low or one time limit has passed.
During routine readiness checks: inspect the crash cart, defibrillator, oxygen, suction, bag-mask equipment and drug expiry dates; know the code-call process.
At collapse: check safety and responsiveness; call for help, activate the emergency response and send for the AED. Check breathing and carotid pulse together within 10 seconds.
Start immediately on a firm, flat support where effective CPR can be delivered. Use the bed’s CPR mode/backboard when appropriate without a long transfer delay.
Allocate compressor, airway, monitor/defibrillator, access/medication and recorder roles. Use closed-loop communication: repeat an instruction, perform it and confirm completion.
100–120/min; depth at least 5 cm, avoiding excessive depth greater than 6 cm. Lower half of sternum; two hands; full recoil.
Ventilation without advanced airway
30:2. Give each breath over about 1 second, just enough for visible chest rise. Prefer a two-person bag-mask seal when staff allow.
Advanced airway
Continuous compressions; 1 breath every 6 seconds. Confirm and monitor tracheal tube position using waveform capnography.
Pauses and fatigue
Keep necessary pauses under 10 seconds; switch compressor about every 2 minutes, sooner if tiring. Do not lean between compressions.
Monitor and record
Rhythm checks about every 2 minutes; record collapse, CPR, shocks, doses, airway and ROSC times. Low/falling ETCO₂ prompts a CPR-quality review.
Attach pads while compressions continue. Clear everyone before shock delivery; manage oxygen safely. Resume compressions immediately after a shock, rather than pausing to look for a pulse. Give oxygen during CPR and avoid excessive bagging.
Defibrillate promptly, then resume CPR for 2 minutes. Obtain IV access first; use IO if IV is unsuccessful/not feasible.
Continue CPR and give epinephrine as soon as possible. Confirm apparent asystole with equipment/lead checks without a prolonged pause.
If VF/pVT persists after the second shock, epinephrine is given during the next CPR cycle; after the third shock, amiodarone or lidocaine is considered.
Do not shock PEA or asystole. Reassess rhythm and treat a new shockable rhythm if it develops.
Adult shock energy: biphasic manufacturer setting (commonly 120–200 J initially); if unknown, use the maximum available setting. Later shocks are at least equivalent; higher doses may be considered. Monophasic: 360 J.
Search for reversible causes: hypovolaemia, hypoxia, acidosis, hypo-/hyperkalaemia, hypothermia; tension pneumothorax, tamponade, toxins, pulmonary thrombosis and coronary thrombosis. Assign someone to check the history and likely cause while CPR continues.
Reassess ABCs, secure and recheck the airway, continue ECG/BP/SpO₂ monitoring and arrange critical-care transfer.
Initially use 100% oxygen until a reliable measurement is available; then titrate toward SpO₂ 90–98%. In the comatose adult, generally target PaCO₂ 35–45 mm Hg. Check an ABG when ventilated.
Avoid hypotension: maintain MAP at least 65 mm Hg, with patient-specific adjustment by the team. Trend lactate, urine output and peripheral perfusion.
Measure core temperature; follow prescribed temperature control and fever prevention. Monitor glucose and electrolytes, skin, lines and possible CPR injuries.
Assess consciousness and seizures, recognising sedation confounds examination. Provide family updates, accurate handover and a team debrief.
Checked 22 October 2026 against the 2025 AHA CPR/ECC guidelines; paediatric recommendations are jointly developed with the AAP. These independent Nursing Medium study notes are not an AHA course, endorsement or certification. Practise CPR through hands-on training; clinical teams follow the current local protocol and patient-specific orders.